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We believe evidence is a duty, not a chore
Our digital treatments aren’t just based on science: They’ve been proven effective in gold-standard clinical trials.
Setting the standard for rigorous clinical evidence
We believe digital treatments must be put to the test as rigorously as traditional medicine. People’s mental health depends on it. That belief not only fuels our commitment to clinical evidence — it also drives our efforts to make research more equitable for underserved populations.
Peer-reviewed publications
Randomized controlled trials (RCTs)
Participants across all evidence papers
Sleepio references in clinical guidelines1-4
Sleepio helped 76% of patients achieve clinical improvement in insomnia
In the world’s first placebo-controlled trial for a digital treatment, Sleepio was shown to be significantly more effective than the placebo. After six weeks, 76% of Sleepio users achieved clinical improvement in insomnia.5
Daylight helped 71% of patients achieve clinical improvement in anxiety
In a landmark study, Daylight demonstrated significantly greater reductions in symptoms of clinical anxiety than the control condition. After 10 weeks, 71% of Daylight patients moved from clinical to non-clinical levels of anxiety, as compared to 33% of those in the control group.6
Featured studies
Sleep and Productivity Benefits of Digital Cognitive Behavioral Therapy for Insomnia: A Randomized Controlled Trial Conducted in the Workplace Environment
Helping employees sleep well: Effects of cognitive behavioral therapy for insomnia on work outcomes
Sleep to Lower Elevated Blood Pressure: A Randomized Controlled Trial (SLEPT)
The effects of improving sleep on mental health (OASIS): a randomised controlled trial with mediation analysis
Effect of Digital Cognitive Behavioral Therapy for Insomnia on Health, Psychological Well-being, and Sleep-Related Quality of Life: A Randomized Clinical Trial
Efficacy of digital CBT for insomnia to reduce depression across demographic groups: a randomized trial
Is digital cognitive behavioural therapy for insomnia effective in treating sub-threshold insomnia: a pilot RCT
Efficacy of Digital Cognitive Behavioral Therapy for the Treatment of Insomnia Symptoms Among Pregnant Women: A Randomized Clinical Trial
A randomized controlled trial of digital cognitive behavioral therapy for insomnia in pregnant women
Efficacy of digital cognitive behavioral therapy for moderate-to-severe symptoms of generalized anxiety disorder: A randomized controlled trial
The effects of digital cognitive behavioral therapy for insomnia on cognitive function: a randomized controlled trial
Efficacy of a digital cognitive behavioral therapy for insomnia in people with low back pain: a feasibility randomized co-twin and singleton-controlled trial
Improving sleep after stroke: A randomised controlled trial of digital cognitive behavioural therapy for insomnia
1. Qaseem, A., Kansagara, D., Forciea, M. A., Cooke, M., & Denberg, T. D. (2016). Management of chronic insomnia disorder in adults: a clinical practice guideline from the American College of Physicians. Annals of Internal Medicine, 165(2), 125-133.
2. Riemann, D., Baglioni, C., Bassetti, C., Bjorvatn, B., Dolenc Groselj, L., Ellis, J. G., … & Spiegelhalder, K. (2017). European guideline for the diagnosis and treatment of insomnia. Journal of Sleep Research, 26(6), 675-700.
3. Wilson, S., Anderson, K., Baldwin, D., Dijk, D. J., Espie, A., Espie, C., … & Sharpley, A. (2019). British Association for Psychopharmacology consensus statement on evidence-based treatment of insomnia, parasomnias and circadian rhythm disorders: an update. Journal of Psychopharmacology, 33(8), 923-947.
4. King’s Technology Evaluation Centre. (2017, November 9). Overview: Health app: SLEEPIO for adults with poor Sleep: Advice. NICE. https://www.nice.org.uk/advice/mib129.
5. Espie, C. A., Kyle, S. D., Williams, C., Ong, J. C., Douglas, N. J., Hames, P., & Brown, J. S. (2012). A randomized, placebo-controlled trial of online cognitive behavioral therapy for chronic insomnia disorder delivered via an automated media-rich web application. Sleep, 35(6), 769-781.
6. Carl, J. R., Miller, C. B., Henry, A. L., Davis, M. L., Stott, R., Smits, J. A., … & Espie, C. A. (2020). Efficacy of digital cognitive behavioral therapy for moderate‐to‐severe symptoms of generalized anxiety disorder: A randomized controlled trial. Depression and Anxiety, 37(12), 1168-1178.